Paolo is a physicist by education but for more than a decade he has specialised in the analysis of high-throughput sequencing data, being particularly interested in the development of algorithms and workflows for alignment and de-novo assembly. He is delighted whenever he can apply those techniques and answer complex biological questions.
He has been a member of several international consortia that focused on studying genome structure and exploring the inner workings of the cell (among them the ENCODE and GEUVADIS projects, and several large sequencing projects). During 5 years spent overseeing bioinformatics and sequencing at the Pirbright Institute, he has researched the comparative genomics of a number of viral families, mechanisms of viral evolution, pathogenicity and attenuation, and the interaction between viruses, vectors and hosts.
He has almost 50 peer-reviewed publications, with more than 25,000 citations according to Google Scholar. He is a member of the British Standards Institution and participates as an invited expert in the work of MPEG and MPAI He is editor of part 6 of the MPEG-G (ISO/IEC 23092) standard on Representation and Compression of Genomic Information. He is a member of the scientific advisory council of Eyam Vaccines and Immunotherapeutics Ltd.