ABSTRACT Summary: Tablet is a lightweight, high-performance graphical view-er for next generation sequence assemblies and alignments. Sup-porting a range of input assembly formats, Tablet provides high-quality visualizations showing data in packed or stacked views, al-lowing instant access and navigation to any region of interest, and whole contig overviews and data summaries. Tablet is both multi-core aware and memory-efficient, allowing it to handle assemblies containing millions of reads, even on a 32-bit desktop machine. Availability: Tablet is freely available for Microsoft Windows, Apple Mac OS X, Linux and Solaris. Fully bundled installers can be down-loaded from http://bioinf.scri.ac.uk/tablet in 32 and 64-bit versions. Contact: bioinf@scri.ac.uk