Deciphering the Genetic Code (1955-66)

1955-1966

Coding theorists are trying to learn the language of the genes

Mapping between messages in two different alphabets.

20 essential amino acids


Image reference

Each amino acid contains an "amine" group (NH3) and a "carboxy" group (COOH) (shown in black in the diagram).
The amino acids vary in their side chains (indicated in blue in the diagram).
The eight amino acids in the orange area are nonpolar and hydrophobic.
The other amino acids are polar and hydrophilic ("water loving").
The two amino acids in the magenta box are acidic ("carboxy" group in the side chain).
The three amino acids in the light blue box are basic ("amine" group in the side chain).


Image reference

Four nucleotide bases


Image references.

Major contributions by George Gamow (1904-1968), Russian-born American physicist who proposed the "Big Bang Theory".

Left: George Gamow in 1948. Middle: Early jottings by Gamow. Right: Two competing coding hypotheses. Image references.


Next
Previous
Start