HOW DOES THIS WORK?

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Antedependence modelling estimates the correlation between the observations at different time points, and then builds this correlation structure into tests for the significance of treatment effects. We could estimate the correlations between all pairs of time points, but it is likely that a simpler model would describe what is going on. We will assume that the effect of the 'past' on an observation is contained in just a few preceding observations. Using antedependence modelling requires two stages:

  1. We decide the order of the model
  2. We assess treatment effects.

For further statistical details about the method see Kenward (1987)

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Antedependence Modelling 27.2.96 : Page 5 of 17