Senior Statistical Scientist
Biomathematics and Statistics Scotland
JCMB, The King's Buildings,
Peter Guthrie Tait Road,
EDINBURGH, EH9 3FD, Scotland, UK.
Tel: +44 (0)131 651 7288
Email: Javier Palarea-Albaladejo
My work in BioSS comprises methodological research, consultancy and training activities. I am based at the BioSS Headquarters in Edinburgh, but also spend some days providing on-site support at the Moredun Research Institute. My areas of specialisation include:
My research work is mostly focused on methods for compositional data analysis and its applications. Compositional data refer to concentration-type multivariate data, typically measured in percentages, part per million, mg/m3, minutes/day, or similar. They represent parts of some whole and, hence, carry only relative information. Importantly, due to the particular constraints they are subject to, standard multivariate data analysis techniques may not be applicable or produce misleading results and interpretations. I have particularly working in principled methods and software to deal with zeros and values below the limit of detection in this context.
Recently, I have been involved in a research project on bacterial discrimination based on mass spectrometry (MS) data. I have been working on robust methods for the automatic identification of faulty and atypical MS proteomic spectra and the determination of optimal parameter settings for the different pre-processing steps involved. These are being integrated in a tailored MS data analysis pipeline in R that facilitates subsequent phylogenetic and chemometric analysis.
I provide statistical and mathematical inputs in support of research in Animal Health and Welfare and other key application areas. This implies working with a wide range of data analysis and modelling tools in partnership with scientists at our collaborating research institutes. Recent projects include the assessment of the effectiveness of a candidate vaccine for the nematode Teladorsagia circumcincta, the characterisation of the immune cell infiltration in placentas of Neospora caninum-inoculated cattle throughout gestation or studying the effects of Toxoplasma gondii immunisation of sheep on tissue parasite burden.
I co-present the Graphical Methods for Multivariate Data BioSS training course for scientists. I also lecture the Multivariate Data Analysis course for 4th year undergraduate and MSc students at the School of Mathematics of the University of Edinburgh.