Document details for 'Optimising the measurement of antimicrobial resistance for use in epidemiology'

Authors Humphry, RW., Evans, J., Webster, C., Tongue, SC., Innocent, G.T. and Gunn, G.J.
Publication details In "Proceedings of the Society of Veterinary Epidemiology and Preventive Medicine". SVEPM.
Publisher details SVEPM
Keywords Antimicrobial resistance, prevalence, test
Abstract Antimicrobial Resistance (AMR) can be measured in different ways. We compare two classes of measurements (sample-level and isolate-level) from faeces samples of livestock. We estimate the agreement of both measurement types. We used simulation to extrapolate onto historic prevalence data, to predict the prevalence we would have found, had we used a different test at that time. The sample-level screening provides higher estimate of prevalence than the isolate-level of prevalence. We propose that such data offers evidence supporting a reappraisal of measuring AMR for epidemiological purposes. In particular we suspect that sample-level screening may be in some epidemiological studies more relevant than the commonly used isolate-level screening.
Last updated 2017-06-27

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